Why a Type 2 Diabetic Should Check

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muthuraji

2016-12-22 11:48:31


A study by Karjalainen et al. in 1992 was conducted to assess whether bovine serum albumin (BSA) was a trigger for IDDM (14). Researchers measured the levels of anti-BSA and anti-ABBOS (specific part of the albumin protein) antibodies in the serum of children with newly diagnosed IDDM, children without IDDM, and blood donors' (14). Antibodies that react to the ABBOS also react with a beta cell surface protein that may represent a target for autoimmune attack (14). All children in the study with IDDM had the highest amount of both antibodies, especially ABBOS, compared to the children without IDDM and blood donors' (14). Antibody levels declined after one or two years of exposure to cow’s milk (14). This suggests that albumin has a section that is capable of reacting with “beta-cell specific surface proteins”, which could contribute to islet cell dysfunction because of molecular mimicry (14). What is molecular mimicry?


http://asuventurecatalyst.org/11-day-diabetes-fix-program-review/
When an antigen is present in the body, T cells latch onto a short segment, consisting of about 10 amino acids. T cells then present the antigen to macrophages that engulf it and break it down into smaller protein fragments. The macrophages bring the fragments to the cell surface where capable T cells can bind to it. This activates the T cells, leading to stimulation in other areas to attack all proteins with similar amino acid segments. Bovine serum albumin has a short amino acid sequence similar to a beta cell surface receptor ICA69 (17) and beta casein shares a similar sequence with a glucose transporter. If molecular mimicry occurs here, then presentation of BSA or beta casein in the body would lead to autoimmune destruction.


http://asuventurecatalyst.org/ez-battery-reconditioning-course-review/

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